Table 3.
Genotype distribution between sarcoidosis and control groups.
| χ2 | p | OR (alleles) | χ2 | 95%CI | p | ||||
|---|---|---|---|---|---|---|---|---|---|
| MMP-2 C735T | CC | CT | TT | C vs.T | |||||
| Control | 40 | 39 | 21 | ||||||
| Sarcoidosis | 54 | 63 | 22 | 1.43 | 0.49 | 1.09 | 0.20 | 0.89–1.20 | 0.66 |
| MMP-7 A181G | AA | AG | GG | A vs. G | |||||
| Control | 47 | 40 | 13 | ||||||
| Sarcoidosis | 52 | 58 | 29 | 3.38 | 0.18 | 0.69 | 3.76 | 0.47–1.01 | 0.053 |
| MMP-9 T1702A | TT | AT | AA | T vs. A | |||||
| Control | 14 | 40 | 46 | ||||||
| Sarcoidosis | 96 | 41 | 2 | 97.71 | <0.0001 | 5.74 | 62.71 | 3.67–8.97 | <0.0001 |
| TIMP-2 G418C | GG | GC | CC | G vs. C | |||||
| Control | 70 | 22 | 8 | ||||||
| Sarcoidosis | 80 | 42 | 17 | 3.90 | 0.14 | 0.74 | 1.72 | 0.48–1.16 | 0.19 |
OR – odds ratio; CI – confidence interval. Chi2 and p values characterize the distribution differences of various polymorphisms within a studied genotype between controls and sarcoidosis patients.