Table 2.

Summary of the results (primary and secondary endpoints) (n=106).

		Group A (bupivacaine)(n=54)		Group B (placebo)(n=52)		p value
		Median	Range	Median	Range
		Primary endpoints
VAS	0 (immediately after awaking)	0	0–7	1	0–9	0.077
	1st post-operative hour	2	0–6	3	0–8	0.126
	2nd post-operative hour	1	0–6	2	0–9	0.09
	3rd post-operative hour	0	0–8	1	0–6	0.105
	4th post-operative hour	0	0–6	1	0–6	0.004
	8th post-operative hour	0	0–8	0	0–8	0.193
	12th post-operative hour	0	0–4	0	0–9	0.02
	16th post-operative hour	0	0–5	0	0–6	0.088
	20th post-operative hour	0	0–5	0	0–4	0.299
	24th post-operative hour	0	0–8	1	0–4	0.352
	36th post-operative hour	0	0–8	0	0–4	0.095
	48th post-operative hour	0	0–7	0	0–6	0.499
			Secondary endpoints
VAS	0–4th post-operative hours	5	0–33	9.5	0–30	0.016
	4–12th post-operative hours	1	0–15	2	0–16	0.011
	12–24th post-operative hours	1	0–18	3	0–15	0.106
	24–48th post-operative hours	3	0–23	5	0–20	0.997
	0–12th post-operative hours	5.5	0–42	11	0–37	0.027
	0–48th post-operative hours	9	0–61	13	0–50	0.076
Intraoperative fentanyl consumption [mg]		0.4	0.2–0.7	0.4	0.25–0.9	0.011
PCA-MF consumption during 1st post-operative hour		0	0–4	0	0–14	0.479
PCA-MF consumption during first 4 post-operative hours		2	0–24	2	0–24	0.517
PCA-MF consumption during first 12 post-operative hours		2	0–26	4	0–24	0.099
PCA-MF consumption from 1st till 4th post-operative hour		2	0–24	2	0–26	0.519
PCA-MF consumption from 4th till 12th post-operative hour		0	0–12	2	0–9	0.02

MF – morphine; VAS – visual analogue scale; PCA – bad demand – number of attempts to launch PCA during lockout; PCA – patient controlled analgesia.