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Effects of ANG II (10−6 M) and PI3-K inhibitor, LY 294002 (1 μM), on IK1 voltage relationship for normal (A) and hypertrophied (B) cardiomyocytes, pretreated with captopril for 14 days. The inset in each graph shows the respective representative current responses at and −120 mV for IK1. Data are presented as average current density ±SEM with n=4–6. * P<0.05 Control vs. ANG II; # P<0.05 Control vs. LY 294002.
