Table 1.
Baseline characteristics of the subjects and the effect of 6-month sulphonylurea treatment in addition to previous metformin monotherapy in the entire group of patients.
| Before treatment | After treatment | p | |
|---|---|---|---|
| Weight (kg) | 84.0±1.8 | 84.3±1.9 | 0.228 |
| BMI (kg/m2) | 30.4±0.4 | 30.5±0.4 | 0.605 |
| FPG (mmol/L) | 8.47±0.14 | 7.12±0.11 | < 0.001 |
| HbA1c (%) | 7.98±0.10 | 6.97±0.06 | < 0.001 |
| Cholesterol (mmol/L) | 5.03±0.15 | 4.90±0.15 | 0.472 |
| LDL cholesterol (mmol/L) | 2.74±0.13 | 2.64±0.10 | 0.542 |
| HDL cholesterol (mmol/L) | 1.20±0.05 | 1.22±0.05 | 0.588 |
| Triglycerides (mmol/L) | 2.07±0.12 | 1.86±0.13 | 0.036 |
Data are expressed as mean ±SE. p-values refer to Student’s tests. BMI – body mass index; FPG – fasting plasma glucose; LDL – low-density lipoprotein; HDL – high-density lipoprotein.