Table 7.
Distribution of genotypes, frequency of alleles of the c.544G>A polymorphism of the heme oxygenase-2 gene and odds ratios (OR) with 95% confidence intervals (95% CI) in age-related macular degeneration and controls among females and males.
| Genotype/allele | Females | Males | ||||
|---|---|---|---|---|---|---|
| Controls N=82 number (%) | Patients N=180 number (%) | OR1 (95% CI) | Controls N=23 number (%) | Patients N=91 number (%) | OR1 (95% CI) | |
| AA | 44 (0.54) | 98 (0.54) | 1.05 (0.54–2.04) | 11 (0.48) | 56 (0.61) | 2.00 (0.64–6.18) |
| AG | 32 (0.39) | 77 (0.43) | 1.05 (0.54–2.06) | 11 (0.48) | 31 (0.34) | 0.45 (0.14–1.44) |
| GG | 6 (0.07) | 5 (0.03) | 0.48 (0.09–2.72) | 1 (0.04) | 4 (0.04) | 1.22 (0.11–12.98) |
| A | 120 (0.73) | 273 (0.76) | 2.06 (0.37–11.57) | 33 (0.72) | 143 (0.79) | 0.82 (0.08–8.70) |
| G | 44 (0.27) | 87 (0.24) | 0.95 (0.49–1.84) | 13 (0.28) | 39 (0.21) | 0.50 (0.16–1.54) |
1
Adjusted for age and family AMD history.