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. 2012 Dec 19;2012:392050. doi: 10.1155/2012/392050

Figure 1.

Figure 1

BMSC-CM confers a significant survival benefit to rats undergoing lethal cisplatin-induced AKI. At hour 0, cisplatin dissolved in physiological saline (0.75 mg/mL) was administered i.p. to male, SAS-SD rats at a lethal dose (7.5 mg/kg). At hours 3, 9, 24, 48, and 72, 1 mL of either physiological saline (n = 12), fibroblast conditioned medium (n = 10) or BMSC-conditioned medium (n = 14) were administered i.v. to the cisplatin-treated AKI rats. They were monitored for survival for 30 days. *P < 0.05 for BMSC-CM compared to both FB-CM and saline by Logrank test.