Figure 5.

Vehicle treated have a greater number of PCNA+ cells 5 days after cisplatin administration. (a) PCNA staining was performed on sections of formalin fixed and paraffin-embedded kidneys from rats administered a lethal dose of cisplatin (7.5 mg/kg) and sacrificed at 5 days following cisplatin administration. The rats were treated at 3, 9, 24, 48 and 72 hours following cisplatin administration, with 1 mL of either physiological saline (n = 4), or BMSC conditioned medium (n = 3) i.v. (b) Quantification of the PCNA positive cells per field of view. Scale bar = 200 μm.