Functional deficits and histological outcomes after MCAO. (A) Percentage of impaired forelimb usage during the rearing test for Wistar rats subjected to MCAO (60 mins, n = 8; 75 mins, n = 6). (B) Percentage of impaired forelimb usage for SD rats subjected to MCAO (60 mins, n = 9; 75 mins, n = 6). (C) The composite neuroscore for Wistar rats subjected to MCAO (60 mins, n = 8; 75 mins, n = 6). (D) The composite neuroscore for SD rats subjected to MCAO (60 mins, n = 9; 75 mins, n = 6). (E) Cavity volume three months post-MCAO (60m, 60 minutes MCAO; 75m, 75 minutes MCAO, * p<0.05 Mann-Whitney U-test). (F) A representative image from each group with a cross section at −1.80 mm from Bregma. (Error bar: S.E.M. The X-axis, D indicates days).