Table 1. Anti-proliferative Activity for 3-Arylcoumarin Derivatives.

	R	SKBr3 (μM)	MCF-7 (μM)
14a	H	38.41 ± 2.31a	28.98 ± 14.96
14b	o-Cl	25.38 ± 9.24	10.58 ± 1.50
14c	m-Cl	9.46 ± 0.84	5.79 ± 0.53
14d	p-Cl	8.24 ± 1.59	3.89 ± 0.61
14e	p-CH3	11.23 ± 1.11	8.60 ± 0.25
14f	p-OCH3	29.93 ± 15.44	16.92 ± 2.34
14g	m-CF3	9.21 ± 1.67	4.64 ± 0.69
14h	p-OCF3	5.78 ± 0.59	4.12 ± 0.37
14i	m-CN	10.60 ± 1.27	8.42 ± 0.12
14j	p-F	43.85 ± 0.32	10.50 ± 0.57
14k	m-F	24.86 ± 9.72	7.67 ± 1.46
14l	3,4-methylenedioxyl	14.80 ± 0.01	8.79 ± 1.32
14m	p-phenoxy	4.43 ± 0.14	1.45 ± 0.11
14n	p-t-butyl	4.42 ± 1.75	2.36 ± 0.30
14o	o-phenyl	15.63 ± 4.35	15.62 ± 0.50
14p	p-phenyl	3.33 ± 0.69	3.08 ± 0.09
16a		0.98 ± 0.01	0.81 ± 0.02
16b		5.84 ± 0.06	4.93 ± 0.06

^aValues represent means ± standard deviations for at least two separate experiments performed in triplicate.