Table 2. Anti-proliferative Activity for 8-Methyl-3-arylcoumarins.
R | SKBr3 (μM) | MCF-7 (μM) | |
---|---|---|---|
20a | H | 14.27 ± 0.54a | 7.72 ± 1.64 |
20b | p-OCH3 | 5.52 ± 1.44 | 1.97 ± 0.11 |
20c | p-Cl | 4.94 ± 0.03 | 1.24 ± 0.06 |
20d | p-F | 7.38 ± 0.23 | 3.83 ± 0.00 |
20e | p-OCF3 | 4.51 ± 0.42 | 1.65 ± 0.16 |
Values represent means ± standard deviations for at least two separate experiments performed in triplicate.