Increased intracellular GSH concentration in activated microglia enhances local inflammation and exacerbates subchronic injury after neonatal stroke. A, At 24 h after reperfusion, volume of injury is unaffected by increased GSH-lip. B, C, At 72 h after reperfusion (B) although several inflammatory chemokines are increased in injured tissue, GSH-lip treatment significantly increased the levels of microglia/macrophage chemoattractants (C). Injury volume is significantly increased by GSH-lip treatment.