Table 2. Mean differences (SE) in DNA methylation levels associated with age, gender and race.
Alu | LINE-1 | |||
Age, gender and race | Additionally adjusted for all SES indicators† | Age, gender and race | Additionally adjusted for all SES indicators† | |
Age | ||||
45 to 54 | Ref | Ref | Ref | Ref |
55 to 64 | −0.01 (0.08) | −0.05 (0.08) | 0.04 (0.13) | 0.06 (0.13) |
65 to 74 | −0.15 (0.08) | −0.08 (0.08) | 0.28 (0.12)* | 0.31 (0.13)* |
75 to 84 | 0.24 (0.11)* | 0.26 (0.11)* | 0.43 (0.16)** | 0.48 (0.17)** |
Gender | ||||
Male | 0.07 (0.06) | 0.07 (0.06) | 0.60 (0.10)*** | 0.62 (0.10)*** |
Female | Ref | Ref | Ref | Ref |
Race category | ||||
White | Ref | Ref | Ref | Ref |
African American | −0.27 (0.09)** | −0.29 (0.10)** | 0.41 (0.14)** | 0.38 (0.16)* |
Hispanic | −0.20 (0.08)* | −0.23 (0.11)* | 0.39 (0.13)** | 0.39 (0.17)* |
SES indicators adjusted were: income, wealth, education, childhood SES.
= p<0.05, ** = p<0.01, *** = p<0.001.