Figure 3. c-Met receptor is involved in HGF-mediated migration in human chondrosarcoma cells.

(A–D) Cells were pretreated with the c-Met inhibitor (3 µM) for 30 min or transfected with c-Met siRNA for 24 h, followed by treatment with HGF for 24 h; cell migration and MMP-2 expression were then examined by Transwell, wound healing, qPCR, and zymography assays. Results are expressed as mean ± S.E. *p<0.05 compared with control; #p<0.05 compared with HGF-treated group.