Table 5. HLA class II allele frequency in the RA cases without SE alleles.
Ro(+)La(−) | Ro(−)La(−) | P | OR | Pc | 95%CI | |
DRB1*0803 | 29 (21.0) | 29 (7.4) | 4.60×10−5 | 3.33 | 0.0008 | (1.91–5.82) |
DQB1*0601 | 47 (34.1) | 79 (20.2) | 0.0016 | 2.05 | 0.0191 | (1.33–3.15) |
DPB1*0501 | 60 (43.5) | 131 (33.4) | 0.0392 | 1.53 | 0.5887 | (1.03–2.28) |
Ro(+)La(+) | Ro(−)La(−) | P | OR | Pc | 95%CI | |
DRB1*1501 | 7 (20.6) | 36 (9.2) | 0.0660 | 2.56 | NS | |
DQB1*0602 | 7 (20.6) | 36 (9.2) | 0.0660 | 2.56 | 0.7915 | |
DPB1*0501 | 15 (44.1) | 131 (33.4) | 0.2579 | 1.57 | NS |
SE: shared epitope, OR: odds ratio, CI: confidence interval, Pc: corrected P value, NS: not significant. Allele frequencies are shown in parenthesis (%). Associations were established by Fisher’s exact test using 2×2 contingency tables.