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. 2013 Jan 8;8(1):e53910. doi: 10.1371/journal.pone.0053910

Table 6. HLA-DPB1 allele frequency in the SLE patients.

Ro(+)La(−) vs. Ro(−)La(−) Ro(+)La(+) vs. Ro(−)La(−)
Ro(+)La(−) Ro(+)La(+) Ro(−)La(−) P OR Pc 95%CI P OR Pc 95%CI
DPB1*01∶01 0 (0.0) 1 (1.1) 0 (0.0) 0.2473 9.20 NS
DPB1*02∶01 49 (19.0) 10 (11.1) 73 (26.6) 0.0393 0.65 0.4711 (0.43–0.97) 0.0022 0.34 0.0283 (0.17–0.70)
DPB1*02∶02 11 (4.3) 3 (3.3) 19 (6.9) 0.1939 0.60 NS 0.3084 0.46 NS
DPB1*03∶01 13 (5.0) 3 (3.3) 10 (3.6) 0.5239 1.40 NS 1.0000 0.91 NS
DPB1*04∶01 6 (2.3) 0 (0.0) 9 (3.3) 0.6045 0.70 NS 0.1198 0.15 NS
DPB1*04∶02 27 (10.5) 7 (7.8) 25 (9.1) 0.6622 1.16 NS 0.8315 0.84 NS
DPB1*05∶01 118 (45.7) 56 (62.2) 91 (33.2) 0.0034 1.69 0.0408 (1.19–2.41) 1.91×10−6 3.31 2.48×10−5 (2.02–5.43)
DPB1*06∶01 1 (0.4) 0 (0.0) 2 (0.7) 1.0000 0.53 NS 1.0000 0.60 NS
DPB1*09∶01 18 (7.0) 4 (4.4) 23 (8.4) 0.6264 0.82 NS 0.2544 0.51 NS
DPB1*13∶01 6 (2.3) 3 (3.3) 10 (3.6) 0.4509 0.63 NS 1.0000 0.91 NS
DPB1*14∶01 8 (3.1) 2 (2.2) 8 (2.9) 1.0000 1.06 NS 1.0000 0.76 NS
DPB1*19∶01 1 (0.4) 0 (0.0) 2 (0.7) 1.0000 0.53 NS 1.0000 0.60 NS
DPB1*38∶01 0 (0.0) 0 (0.0) 2 (0.7) 0.4995 0.21 NS 1.0000 0.60 NS

SLE: systemic lupus erythematosus, Ro(+)La(−): anti-Ro/SS-A-positive but anti-La/SS-B-negative, Ro(+)La(+): anti-Ro/SS-A- and anti-La/SS-B-positive, Ro(−)La(−): anti-Ro/SS-A- and anti-La/SS-B-negative SLE patients. OR: odds ratio, CI: confidence interval, Pc: corrected P value, NS: not significant. Allele frequencies are shown in parenthesis (%). Associations were established by Fisher’s exact test using 2×2 contingency tables.