Table 6. HLA-DPB1 allele frequency in the SLE patients.
Ro(+)La(−) vs. Ro(−)La(−) | Ro(+)La(+) vs. Ro(−)La(−) | ||||||||||
Ro(+)La(−) | Ro(+)La(+) | Ro(−)La(−) | P | OR | Pc | 95%CI | P | OR | Pc | 95%CI | |
DPB1*01∶01 | 0 (0.0) | 1 (1.1) | 0 (0.0) | 0.2473 | 9.20 | NS | |||||
DPB1*02∶01 | 49 (19.0) | 10 (11.1) | 73 (26.6) | 0.0393 | 0.65 | 0.4711 | (0.43–0.97) | 0.0022 | 0.34 | 0.0283 | (0.17–0.70) |
DPB1*02∶02 | 11 (4.3) | 3 (3.3) | 19 (6.9) | 0.1939 | 0.60 | NS | 0.3084 | 0.46 | NS | ||
DPB1*03∶01 | 13 (5.0) | 3 (3.3) | 10 (3.6) | 0.5239 | 1.40 | NS | 1.0000 | 0.91 | NS | ||
DPB1*04∶01 | 6 (2.3) | 0 (0.0) | 9 (3.3) | 0.6045 | 0.70 | NS | 0.1198 | 0.15 | NS | ||
DPB1*04∶02 | 27 (10.5) | 7 (7.8) | 25 (9.1) | 0.6622 | 1.16 | NS | 0.8315 | 0.84 | NS | ||
DPB1*05∶01 | 118 (45.7) | 56 (62.2) | 91 (33.2) | 0.0034 | 1.69 | 0.0408 | (1.19–2.41) | 1.91×10−6 | 3.31 | 2.48×10−5 | (2.02–5.43) |
DPB1*06∶01 | 1 (0.4) | 0 (0.0) | 2 (0.7) | 1.0000 | 0.53 | NS | 1.0000 | 0.60 | NS | ||
DPB1*09∶01 | 18 (7.0) | 4 (4.4) | 23 (8.4) | 0.6264 | 0.82 | NS | 0.2544 | 0.51 | NS | ||
DPB1*13∶01 | 6 (2.3) | 3 (3.3) | 10 (3.6) | 0.4509 | 0.63 | NS | 1.0000 | 0.91 | NS | ||
DPB1*14∶01 | 8 (3.1) | 2 (2.2) | 8 (2.9) | 1.0000 | 1.06 | NS | 1.0000 | 0.76 | NS | ||
DPB1*19∶01 | 1 (0.4) | 0 (0.0) | 2 (0.7) | 1.0000 | 0.53 | NS | 1.0000 | 0.60 | NS | ||
DPB1*38∶01 | 0 (0.0) | 0 (0.0) | 2 (0.7) | 0.4995 | 0.21 | NS | 1.0000 | 0.60 | NS |
SLE: systemic lupus erythematosus, Ro(+)La(−): anti-Ro/SS-A-positive but anti-La/SS-B-negative, Ro(+)La(+): anti-Ro/SS-A- and anti-La/SS-B-positive, Ro(−)La(−): anti-Ro/SS-A- and anti-La/SS-B-negative SLE patients. OR: odds ratio, CI: confidence interval, Pc: corrected P value, NS: not significant. Allele frequencies are shown in parenthesis (%). Associations were established by Fisher’s exact test using 2×2 contingency tables.