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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2012 Feb 10;18(9):1368–1377. doi: 10.1016/j.bbmt.2012.02.002

Table 4.

Summary of Current Series and Published Data on Bone Marrow Transplants for CGD.

Source Center or Group Donor Source (# of patients) Conditioning Median Follow-up (months) OS% Engraftment % Patients achieving high (>90%) donor chimerism
Tewari, 2012 Duke University Medical Center R-M-BM (5) MAC 97 100 100 100
Gozdzik, 2011 Univeristy Children’s Hospital, Cracow R-M-BM (2), U-M-BM (3), U-MM-BM(1) MAC (5), RIC (1) Mean: 20 100 100 100
Soncini, 2009 UK Northern Supra Regional HSCT Unit R-M-BM (9), U-M-BM (6), U-M-PBSC (2), U-MM-PBSC (1) MAC(14), RIC(4) 61 88 MAC(100), RIC (50) MAC: 100
RIC: 75
NA
Schuetz, 2009 Universtiy Hospital Ulm R-M-BM (3), U-M-BM (6), U-M-PBSC(3) MAC (9), RIC (3) 53 75 MAC(57), RIC (100) MAC: 100
RIC: 66
92
Güngör, 2005 University Children’s Hospital of Zurich M-U-BM(1), M-R-BM(2) RIC 17 100 100 100
Seger, 2002 EBMT R-M-BM(25), U-M-BM (2) MAC(23), RIC (4) 24 85 MAC(92), RIC (75) MAC: 95
RIC: 50
85
Horwitz, 2001 National Institutes of Health, Bethesda R-M-BM(10) RIC 17 70 80 60

R-M-BM: Related matched bone marrow, U-M-BM: Unrelated matched bone marrow; U MM-BM: Unrelated mismatched bone marrow; U-M-PBSC: Unrelated matched peripheral blood stem cells; U-MM-PBSC: Unrelated mismatched peripheral blood stem cells. MAC: Myeloablative conditioning.