Table 1.
Strains | Range of BBE concentrations | ||||
---|---|---|---|---|---|
Water | 175 μg/mL | 350 μg/mL | 700 μg/mL | 1400 μg/mL | |
S. oralis | -3.1 (8.6) | 3.6 (2.7) | -0.5 (9.3) | -7.9 (10.5) | 8.6 (7.8) |
S. gordonii | 2.3 (3.6) | -1.0 (10.2) | -1.6 (4.5) | -11.1 (13.3) | -11.6 (5.1) |
S. mutans | 5.2 (9.6) | 16.1 (5.9) | 23.9 (4.0)* | 31.4 (3.4)* | 27.5 (1.7)* |
A. naeslundii | 3.3 (12.2) | 6.5 (13.3) | 12.9 (7.0) | 11.7 (10.8) | 14.0 (8.7) |
A. viscosus | -7.1 (7.0) | 0.4 (5.2) | 3.8 (4.9) | -3.4 (8.1) | 10.3 (7.3) |
V. parvula | -0.2 (2.1) | -0.4 (2.4) | -0.4 (2.6) | -0.03 (2.6) | -0.003 (2.1) |
P. intermedia | 0.3 (2.3) | 0.1 (2.3) | 0.4 (2.1) | 0.2 (2.6) | 0.3 (2.2) |
A. actinomycetecomintans | 7.6 (20.0) | -7.2 (17.8) | -14.2 (14.3) | -19.5 (10.3) | -9.6 (10.4) |
P. gingivalis | 1.6 (6.9) | 13.8 (5.5) | 27.0 (5.3)* | 40.7 (2.0)* | 43.6 (2.5)* |
F. nucleatum | 1.7 (5.7) | 0.0 (7.0) | 4.5 (9.4) | 40.9 (18.5)* | 83.5 (5.2)* |
Data are mean percentage reductions of metabolic activity following treatment with a range of BBE concentrations. Results from at least two independent experiments performed in triplicate for each strain of bacteria. Standard deviations shown in parenthesis. Values significantly different (p ≤ 0.05) between water treatment vs. BBE extract are identified with an asterisk.
Percentage of metabolic activity inhibition for F. nucleatum and P. gingivalis exposed to 0.1% chlorhexidine for 24 h were 29.1(13.7) and 57(5.9), respectively.