Table 5.

Results of multi level model testing of TEASAP longitudinal validity

	UMM	Model A	Model B	Model C	Model D1	Model D2
Fixed Effects
Intercept	.279(.086)* **	.230(.083)* *	.221(.079)* *	.215(.079)* *	.114(.060)	.128(.127)
Age			−.115(.072)	Dropped	Dropped	Dropped
Drug				.259(.170)a	Dropped	Dropped
Randomization				.193(.180)b
Total					.273(.057)*
Score-M					**
Total					.271(.101)*	.087(.049)+
Score-						.128(.055)*
BC						.240(.060)*
Irritability-						**
M						.016(.044)
Akathisia-						.261(.058)*
M						**
Disinhibition-M
Mania-M
Self-Injury-M
Random
Effects	.831(.043)*	.800(.042)*	.800(.042)*	.801(.042)*	.711(.039)*	.511(.035)*
Residual	**	**	**	**	**	**
Time		.048(.026)+	.048(.025)+	.049(.026)+	.042(.024)+	.012(.016)
(linear)					.272(.111)*
Total						.212(.118)+
Score-BC						.418(.214)+
Irritability-						.733(.269)*
BC						**
Akathisia-						.354(.178)*
BC						*
						.401(.171)*
Disinhibition-BC
Mania-BC
Self Injury-BC
Fit Statistics
-2LL	2322.419	2314.350	2311.840	2311.947	2230.117	2170.982
AIC	2328.419	2322.350	2321.840	2323.947	2244.117	2198.982
BIC	2342.616	2341.279	2345.501	2352.34	2272.192	2265.133
Overall R2	47.80%	53.90%	53.80%	53.71%	61.80%	77.60%
ΔFixed		17.36%	3.8%	6.5%	50.66%	44.55%
Pseudo R2		3.71%	0.05%	0%	11.13%	36.09%
ΔRandom
Pseudo R2

Note

⁺p<.08

^*p<.05,

^**p<.01,

^***p<.001.

^aSlow titration arm,

^bRegular titration arm; compared to placebo arm. M= Mean, BC=Baseline Centered