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Pitx2 isoforms and alleles. (A) Map of the Pitx2 gene showing exons, introns, and isoforms. Arrows indicate alternate transcription start sites. (B) Summary of exon usage and size of Pitx2 isoforms. (C) List of mouse Pitx2 alleles used to generate unique Pitx2 deficient embryos. Pitx2 isoforms that remain intact are listed on the right.
