Table 1.
WT | Kel-KO | Xk-KO | Kel/Xk-KO | |
---|---|---|---|---|
|
||||
MCV, fL | 46.6±0.3 | 48.3±0.1* | 46.4±0.6 | 49.8±0.7* |
CHCM, g/dL | 28.9±0.3 | 26.8±0.6* | 29.2±0.2* | 27.7±0.1* |
Reticulocytes, % | 2.71±0.2 | 3.15±0.1* | 2.9±0.5 | 3.6±0.2* |
RDW, % | 13.0±0.4 | 13.4±0.2 | 13.0±0.5 | 12.8±0.8 |
HDW, g/dL | 1.99±0.1 | 2.8±0.1* | 2.08±0.0 | 1.82±0.0 |
Determination of hematological parameters was performed using ADVIA (Bayer, NJ) with mouse software.
MCV, mean cellular volume; CHCM, corpuscular hemoglobin concentration mean; RDW, red cell distribution width; HDW, hemoglobin distribution width. WT, wild-type n=10; Kel-KO, Kel knockout n=10; Xk-KO, Xk knockout n=10; Kel/Xk-KO, double knockout n=5,
p<0.03 compared to WT, ANOVA analysis. Values represent the mean±SD.