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. Author manuscript; available in PMC: 2014 Jan 23.
Published in final edited form as: J Mol Biol. 2012 Nov 23;425(2):214–221. doi: 10.1016/j.jmb.2012.11.022

Figure 4. P60 is regulated after monomer enrichment on the microtubule.

Figure 4

Binding to the microtubule is unaffected by modification at serine 131 but microtubule severing and microtubule stimulated ATPase activity is inhibited. The point of regulation by phosphophorylation at serine 131 must come after monomers of p60 are bound to the microtubule. We hypothesize that oligomerization is regulated to control levels of severing activity.