TABLE 3.
Overall multivariable linear regression model
Covariate | Coefficient | P |
---|---|---|
Age at diagnosis (years) | 0.02 | 0.74 |
Education | ||
College degree vs high school | 1.04 | 0.49 |
High school degree vs high school | 1.45 | 0.36 |
College vs high school | −0.22 | 0.9 |
Race/ethnicity | ||
African American vs Caucasian | −4.36 | 0.07 |
Asian/Pacific Islander vs Caucasian | −4.39 | 0.33 |
Latino vs Caucasian | −4.77 | 0.2 |
Other/unknown vs Caucasian | 0.83 | 0.81 |
Married/partnered (yes vs no) | −0.99 | 0.53 |
PSA level at diagnosis (ng/mL) | 0.03 | 0.52 |
Biopsy Gleason grade | ||
7 (3+4) vs 2–6 | −1.03 | 0.38 |
7 (4+3) vs 2–6 | 1.29 | 0.45 |
8–10 vs 2–6 | 1.96 | 0.32 |
Clinical T-stage | ||
cT2 vs cT1 | −0.27 | 0.76 |
cT3 vs cT1 | 2.76 | 0.64 |
Primary treatment | ||
PADT vs RP | −2.47 | 0.27 |
RT vs RP | −0.58 | 0.65 |
Any neoadjuvant/adjuvant treatment | −1.28 | 0.33 |
Time from diagnosis to treatment (months) | 0.1 | 0.75 |
Baseline body mass index | 0.01 | 0.95 |
Baseline number of comorbidities | −0.73 | 0.04 |
Baseline SF-36 MCS | 0.14 | < 0.01 |
Baseline SF-36 PCS | 0.13 | 0.02 |
Baseline fear of cancer recurrence | −0.16 | < 0.01 |
PCI sexual function decline | −1.81 | 0.04 |
PCI bowel function decline | −2.84 | < 0.01 |
PCI urinary function decline | −2.15 | 0.02 |
MCS, Mental Component Summary; PADT, primary androgen deprivation therapy; PCI, Prostate Cancer Index; PCS, Physical Component Summary; RP, radical prostatectomy; RT, radiation therapy; SF-36, 36-item short-form health survey.