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AFM images of hIAPP fibers with and without calcium ions. (A and B) Top: AFM images of POPC/POPS (7:3) SLBs after exposure to 2 μM hIAPP alone for 2 hr (A) and 24 hr (B). (C and D) Bottom: AFM images of POPC/POPS SLBs incubated with both 2 μM hIAPP and 100 μM Ca2+ ions for 2 hr (C) and 24 hr (D). All experiments were performed in 10 mM HEPES buffer, 100 mM NaCl, pH 7.4 at 25°C.
