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. 2012 Dec 26;46(6):576–582. doi: 10.4132/KoreanJPathol.2012.46.6.576

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© 2012 The Korean Society of Pathologists/The Korean Society for Cytopathology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1 — Representative histologic (A, C, E) and cytologic (B, D, F) features of pleomorphic carcinoma. (A) Large cell carcinoma. The pleomorphic epithelioid cells form a solid sheet without glandular or squamous differentiation. (B) Large cell carcinoma. The cluster is composed of pleomorphic large cells with abundant thick cytoplasm. (C) Spindle cell component. The neoplastic spindle cells are arranged in interlacing fascicles. (D) Spindle cell component. The pleomorphic spindle cells are arranged in fascicles with hyperchromatic nuclei (inset). (E) Giant cell component. The tumor cells are pleomorphic and discohesive. (F) Giant cell component. Mono-, bi-, and multi-nucleated giant cells reveal bizarre and hyperchromatic nuclei and prominent nucleoli.