Table 4.
Summary of phage display applications in Eimeria research.
Target | Library | Result | References |
---|---|---|---|
Eimeria sporozoites/live | Random peptides | Identification of PW2 peptide with activity against E. acervulina and E. tenella sporozoites | da Silva et al., 2002 |
E. tenella sporozoites/cryopreserved | Chicken scFV antibodies from E. tenella immune birds | Isolation of an scFV antibody that binds specifically to E. tenella sporozoites | Abi-Ghanem et al., 2008 |
Cryopreserved E. acervulina merozoites | Chicken scFV antibodies from E. tenella immune birds | Identification of antibody fragments with high specificity and binding capacity for soluble antigens and intact fixed merozoites | Zhao et al., 2010 |
Anti-GAM56 protein | E. tenella cDNA phage display | Identification of EtGAM22 expressed predominantly at the gametocyte stage | Krucken et al., 2008 |