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ME tumors characterized by EWSR1-PBX1 fusion: (A) 37-year old male with a left hip lesion, showing a bland spindle cell proliferation embedded in a fibrotic stroma (200x); (B) 6-year old female with a locally recurrent forearm mass showing bone invasion, composed of uniform epithelioid cells with scant clear cell cytoplasm (200x); (C) partial karyotype showing a t(1;22)(q23;q12), confirmed by FISH to have a rearrangement of (D) PBX1 and (E) EWSR1.
