The phenotype of the “stem” cell continually and reversibly changes with passage through cell cycle. (Abbreviations: CLP, common lymphoid progenitor; CMP, common multipotent progenitor; LT-HSC, long-term hematopoetic stem cell; ST-HSC, short-term hematopeotic stem cell; GMP, granulocyte-macrophage progenitor; ERMegPP, megakaryocye erythroid progenitor; MP, multipotent progenitor.)