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miR‐30b‐c targets Runx2 through a site at the 3′ ‐UTR. A reporter plasmid construct containing the Runx2 3′ ‐UTR and pre–miR‐30b, pre–miR‐30c, or both, were co‐transfected into COS7 cells. A scrambled miRNA sequence (SS) served as the negative control. In this assay, decreased luminosity indicates miRNA binding to the 3′ ‐UTR. Relative fluorescence units (RFUs) were compared against SS. *P<0.04 vs SS. miR indicates microRNA.
