Table 8.

HRs for Mortality Outcomes During the Study Period, According to Other Biochemical Indices of Insulin Resistance (N=5152)

	Fasting Insulin Levels, pmol/L	HOMA‐IR	QUICKI
Adjusted HR for cardiovascular mortality (95% CI)
Quartile 1	Referent	Referent	Referent
Quartile 2	0.85 (0.59 to 1.21)	0.93 (0.61 to 1.42)	1.00 (0.71 to 1.40)
Quartile 3	1.10 (0.70 to 1.71)	1.13 (0.73 to 1.74)	0.82 (0.57 to 1.18)
Quartile 4	1.08 (0.66 to 1.77)	1.13 (0.72 to 1.78)	0.88 (0.56 to 1.38)
Adjusted HR for overall mortality (95% CI)
Quartile 1	Referent	Referent	Referent
Quartile 2	0.95 (0.81 to 1.12)	1.00 (0.83 to 1.20)	0.95 (0.78 to 1.15)
Quartile 3	1.29 (0.98 to 1.71)	1.29 (1.02 to 1.64)	0.74 (0.56 to 0.97)
Quartile 4	1.35 (1.00 to 1.81)	1.36 (1.01 to 1.82)	0.74 (0.55 to 0.99)

CI indicates confidence interval; HR, hazard ratio; HOMA‐IR, fasting plasma glucose (mg/dL)×fasting serum insulin levels/405; QUICKI index, 1/[log (fasting serum insulin)+log (fasting plasma glucose)].

Model was adjusted for age, sex, race, waist‐to‐hip ratio, body mass index, blood pressure, total cholesterol, triglycerides, high density lipoprotein, history of stroke, heart attack, peripheral arterial disease, family history of diabetes and heart attack, history of chest pain, level of education, smoking status, level of physical activity, alcohol use in last month, C‐reactive protein level, urinary albumin/creatinine ratio, glomerular filtration rate, and glycated hemoglobin levels. Bold values represent statistically significant results at P values of <0.05.