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B cell development requires the activity of p110α or p110δ. (A) Flow cytometric analysis of lymphocytes from the bone marrow of the indicated mice. The percentages in each quadrant or gate are averages; p110αfl (n = 10 mice), CD2Cre-p110αfl (n = 6 mice), p110δD910A (n = 8 mice), CD2Cre-p110αflδD910A (n = 13 mice). (B) Total numbers (± SEM) of each B cell subset from two femurs of the indicated mice.
