Table 1.

Neuronal adhesion on CNT coated surfaces.

	References	CNT surface	CNT modification	In vitro bio-testing scheme	Results
MWCNTs
	Mattson et al., 2000	MWCNTs coated cover slip	Pristine	Embryonic rat hippocampal cultures	Neuronal growth
			4-HNE		Increased neurites branching and length on modified CNTs
	Hu et al., 2004	MWCNTs coated cover slip	COO	Rat hippocampal cultures	Increased neurites branching and length on positively charged CNTs
			PABS
			EN
	Matsumoto et al., 2007	MWCNTs soluble in growth medium	NGF or BDNF	Embryonic chick DRG neurons	CNT attached factors and soluble factors had similar effect on neurite outgrowth
	Gabay et al., 2005a,b	MWCNT islands directly grown on catalyst patterned substrate	Pristine	Rat cortical cultures	Neuronal aggregation on CNT islands and formation of a neurite interconnected network
	Galvan-Garcia et al., 2007	Directionality oriented MWCNT sheets and yarns	Pristine	Rat shwan cells Mice primary cortical and cerebral neurons Mice DRG neurons	Multiple cell types permissiveness Neuronal interaction with CNTs may be affected by CNT purity and 3D structure
	Zhang et al., 2005	Vertical MWCNT arrays directly grown on catalyst patterned substrate	PLL	H19-7 cell line	Preferred guided neurite growth on longer flexible MWCNTs
	Xie et al., 2006	MWCNT mats	COOH	Rat DRG neurons	Longer neurites on modified CNTs Neurites intertwined with CNTs
	Sorkin et al., 2009	MWCNT islands directly grown on catalyst patterned substrate	Pristine	Rat cortical cultures Locust ganglion cells	Neurite morphology on high density CNT islands was curled and entangled
SWCNTs
	Hu et al., 2005	SWCNT coated cover slip	Pristine	Rat hippocampal cultures	Increased neurite outgrowth and branching on modified CNTs
			PEI
	Gheith et al., 2005	SWCNT-PAA coated cover slip (by LBL)	Amphiphilic polymer	NG108 cell line	Neuronal growth
	Liopo et al., 2006	SWCNT coated PET film	4-tertbutylphenyl	NG108 cell line Rat primary peripheral neurons	Decreased neurites branching and length on modified CNTs
			4-benzoic acid
	Malarkey et al., 2009	SWCNT coated cover slips	PEG	Rat hippocampal cultures	Longer neuritis on less conducting films Larger cell bodies on more conductive films
CNFs
	Nguyen-Vu et al., 2006	VACNFs directly grown on an catalyst patterned substrate	PPy	PC12 cell line	Soft PPy contributes to better mechanical coupling between cells and CNTs
	Nguyen-Vu et al., 2007		PPy and NGF