Figure 1.

Major steps of functional connectivity analysis. Parcellation of the brain into areas based on the anatomical atlas and extraction of demeaned time series BOLD signal from each area (A), construction of correlation matrices (B) thresholding and binarization of correlation matrices; generation of binary adjacency matrices (C) visualized in (D), analysis of topology and microcircuit patterns (E). In the blue boxes are the names of main software tools used at relevant stages. Section “Materials and Methods” for further details.