TABLE 2.
Tunnels Are Closer to Synapses Than Are Sheets1
| Recon | Mean distance (nm) | SEM (nm) | SD of distance (nm) | No. of vertices |
|---|---|---|---|---|
| C, sheet | 728 | 0.47 | 454 | 922,397 |
| C, tunnel | 706 | 0.66 | 436 | 433,498 |
| D, sheet | 401 | 0.17 | 157 | 881,150 |
| D, tunnel | 385 | 0.21 | 146 | 467,270 |
| E, sheet | 743 | 0.59 | 465 | 615,596 |
| E, tunnel | 702 | 0.50 | 433 | 739,397 |
| F, sheet | 406 | 0.19 | 159 | 714,478 |
| F, tunnel | 383 | 0.18 | 145 | 630,458 |
| G, sheet | 746 | 0.61 | 469 | 595,424 |
| G, tunnel | 700 | 0.49 | 429 | 755,893 |
| H, sheet | 414 | 0.21 | 162 | 568,999 |
| H, tunnel | 381 | 0.16 | 145 | 774,364 |
Also see Figure 7. The straight-line distance from each vertex to the centroid of the closest synapse was measured. In all reconstructions, vertices facing tunnel ECS are closer to a synapse on average than vertices facing sheets. In Figure 7 we observed that perisynaptic ECS is tunnel-enriched. Together these results suggest that synapses are more closely associated with tunnels than sheets. Recon refers to reconstruction labels in Figure 2.