Fig. 6.

Ability of human plasma and recombinant apoA-II to promote cellular cholesterol efflux via ABCA1. The apoA-II samples were used as cholesterol acceptors from cholesterol-labeled RAW264.7 macrophages. The proteins were added to the media at concentrations in the 1–10 μg/ml range for 6 h. Percent efflux was calculated by dividing the efflux media counts by the total counts (n = 3; error bars represent 1 SD). Closed and open circles: Human plasma and recombinant apoA-II in the presence of cAMP, respectively. Closed and open triangles: Human plasma and recombinant apoA-II without cAMP, respectively.