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. 2013 Jan 9;6:79. doi: 10.3389/fnsys.2012.00079

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Copyright © 2013 Alitto and Dan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Effect of mecamylamine on BF modulation of cortical neurons. Left column, post-mecamylamine vs. pre-mecamylamine response amplitude (dF/F). Each symbol, one cell; error bar, ±SEM. Right column, average response from all responsive cells in each subtype; gray, pre-mecamylamine; black, post-mecamylamine. (A) Excitatory neurons, increased 27% post-mecamylamine (p = 0.05, n = 23). (B) VIP+, decreased by 57% (p < 0.0001, n = 25). (C) Layer 1, decreased by 80% (p < 0.01, n = 6). (D) PV+ with positive responses, increased by 39% (p = 0.17, n = 7). (E) PV+ with negative responses, decreased by 210% (p < 0.001, n = 7).