Figure 7.

Worsening tumor grade correlates with increased pSrc and Id1 expression levels and increased Id1 expression correlates with poor overall survival in pancreatic cancer patients. (A) Increased tumor grade level demonstrates a clear correlation with higher pSrc expression levels (score) with a Spearman correlation estimate of 0.31 (P < .001). (B) Increased tumor grade level is associated with increased Id1 expression (score) with a Spearman correlation estimate of 0.29 (P < .001). (C) Patients with high histologic grade have significantly worse survival than patients with low histologic grade (P = .0235). (D) Dichotomizing Id1 scores into low and high scores using the 75% score demonstrates significant correlation with overall patient survival, with high Id1 expression levels resulting in a worse overall survival (P = .0388). (E) Increased tumor grade level demonstrates a significant correlation with increased Id1 expression (algorithmic densitometric analyses) with Spearman correlation estimate of 0.24 (P = .0042). (F) Dichotomizing Id1 scores (determined by quantitative algorithm) into low and high scores with 75% score demonstrates a significant correlation with overall patient survival with high Id1 expression levels resulting in a worse overall survival (P = .0519).