. 2012 Dec;14(12):1190–1202. doi: 10.1593/neo.121258

Table 1.

Effect of c-Myc on RS and Coding Joining.

Cell Line	pJH200 (RS Joining)				pJH290 (Coding Joining)
	(Amp^r + Cam^r)/Amp^r	%	Relative Level	Fidelity %	(Amp^r + Cam^r)/Amp^r	%	Relative Level
Experiment 1
HO15.19
Vector	95/12111	0.78	1	100 (14/14)	103/6250	1.64	1
WT	24/40101	0.06	0.08	28 (4/14)	10/15430	0.06	0.04
ΔMBI	30/38400	0.08	0.1	42 (6/14)	12/22800	0.05	0.03
ΔMBII	105/14101	0.74	0.95	100 (14/14)	172/10867	1.58	0.95
ΔHLH	24/12577	0.19	0.24	35 (5/14)	17/16110	0.1	0.06
Experiment 2
HO15.19
Vector	119/14500	0.82	1	100 (14/14)	161/17980	0.89	1
WT	33/40110	0.08	0.09	42 (6/14)	52/44560	0.12	0.12
ΔMBI	51/45890	0.11	0.13	28 (4/14)	111/33420	0.33	0.37
ΔMBII	77/10900	0.7	0.85	100 (14/14)	255/29840	0.85	0.95
ΔHLH	22/25990	0.08	0.09	35 (7/14)	67/33220	0.2	0.22
Experiment 3
HO15.19
Vector	129/19500	0.66	1	100 (14/14)	322/36745	0.88	1
WT	32/32300	0.09	0.13	57 (8/14)	59/32412	0.18	0.2
ΔMBI	21/20310	0.1	0.15	64 (9/14)	119/38567	0.31	0.35
ΔMBII	48/8430	0.57	0.86	100 (14/14)	234/31010	0.75	0.85
ΔHLH	45/35400	0.13	0.2	57 (8/14)	131/45991	0.28	0.32
Experiment 4
HO15.19
Vector	145/23500	0.62	1	100 (14/14)	245/31300	0.8	1
WT	25/30800	0.08	0.12	57 (8/14)	78/43200	0.18	0.23
ΔMBI	21/20100	0.1	0.16	71 (10/14)	87/28400	0.31	0.38
ΔMBII	50/10300	0.49	0.79	100 (14/14)	153/23200	0.66	0.82
ΔHLH	43/32300	0.13	0.21	71 (10/14)	178/63800	0.27	0.34

RS and coding joins were measured in HO15.19 cells expressing WT or each of the c-Myc deletion mutants. Four independent transfection experiments were carried out with each cell line.