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. Author manuscript; available in PMC: 2013 Jan 9.
Published in final edited form as: Electrophoresis. 2009 Oct;30(19):3324–3333. doi: 10.1002/elps.200900317

Table 4.

Qualitative Assessment of Microchip Performance

Analytical Parameters
Fabrication Procedure
Remarks
Sensitivity1 Limit of Detection2 Noise3 Process Cost Use of
Hazardous
Chemicals4
PPF End - Channel Best Best Low Simplest Moderate No Requires fused silica substrate; high temperature furnace
Carbon Fiber End - Channel Good Fair Fair Simple Inexpensive No Requires skill to embed carbon fiber into PDMS substrate
Palladium End - Channel Good Fair High Complex Expensive Yes Deposition system required; use of expensive or rare metals
Palladium Off - Channel Poor Fair Fair Complex Expensive Yes Deposition system required; use of expensive or rare metals
Carbon Ink Off - Channel Fair Good Lowest Simple Inexpensive Yes Electrode size is limited by PDMS aspect ratio; thick films can be highly resistive
Carbon Ink End - Channel Poor Fair Lowest Simple Inexpensive No Electrode size is limited by PDMS aspect ratio; thick films can be highly resistive
1

Slope of the calibration curve

2

Calculated for S/N=3

3

Based on average peak-to-peak baseline noise

4

Use of HF and/or aqua regia solutions