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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Dev Biol. 2012 Nov 16;373(2):422–430. doi: 10.1016/j.ydbio.2012.10.008

Figure 4. TIF1γ deficiency promotes myelopoiesis while inhibiting erythropoiesis.

Figure 4

(A) Increased number of GMPs in vav-cre; tif1γfl/fl mice at 3-month old. The absolute numbers of cells are shown as mean ± SD from 4 mice in each group (** q ≤ 0.001).

(B) Heat map showing regulation of genes representative of the erythroid signature and the myeloid signature from GMPs derived from vav-cre; tif1γfl/+ (con) and vav-cre; tif1γfl/fl (KO) mice.

(C) Increased HSC levels in vav-cre; tif1γfl/fl mice at 3-month old. The absolute numbers of cells are shown as mean ± SD from 4 mice in each group (* q ≤ 0.05).