Figure 2.
Fodrin cleavage is not required for other hallmarks of cell death in galectin-1 treated Jurkat T cells. A) Annexin V binding to Jurkat and J45.01 cells treated with buffer control (thin line) or galectin-1 (thick line). B) Annexin V binding to Jurkat cells treated with buffer control (thin line) or galectin-1 (thick line) in the absence of presence of the indicated calpain inhibitors. C) DNA degradation detected by TUNEL in control or galectin-1 treated cells in the absence or presence of the indicated calpain inhibitors. Data are representative (A and B) or mean +/− SD of triplicate samples (C) from one of three independent experiments.