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. Author manuscript; available in PMC: 2013 Jan 9.
Published in final edited form as: J Immunol. 2009 Jun 1;182(11):7001–7008. doi: 10.4049/jimmunol.0804329

Figure 5.

Figure 5

Fodrin cleavage promotes phagocytosis of dying cells. A) Jurkat and J45.01 cells were labeled with CFSE prior to addition of buffer control or galectin-1 for 6 hrs. T cells were added to RAW 264.7 macrophage monolayers for 1 or 3 hr. Phagocytosis of labeled T cells was visualized by confocal microscopy. B) Phagocytotic index of macrophages with Jurkat or J45.01 cells. * at 1 hr, p = 0.39 for Jurkat vs. J45.01 cells treated with galectin-1. ** at 3 hr, p < 0.02 for Jurkat vs. J45.01 cells treated with galectin-1. (C) The fraction of macrophages with ingested cells. * at 1 hr, p = 0.02 for Jurkat vs. J45.01 cells treated with galectin-1. ** at 3 hr, p < 0.01 for Jurkat vs. J45.01 cells treated with galectin-1. For (B) and (C), values are mean +/− SD of triplicate samples from one of three independent experiments.