Table 1.

Effect of bee venom Plase A₂ on human and bovine erythrocytes

Phospholipid class	Human erythrocytes, % of total phospholipids		Bovine erythrocytes, % of total phospholipids
	Control	Treated	Control	Treated
LPC	1.0  ± 0.1	18.7  ± 1.7**	1.7  ± 0.2	1.6  ± 0.2
SM	25.0  ± 2.0	26.9  ± 2.2	47.6  ± 3.8	46.3  ± 3.1
PC	29.6  ± 2.6	12.2  ± 1.2**	4.5  ± 0.5	4.7  ± 0.4
PI + PS	14.6  ± 1.7	12.7  ± 1.7	13.6  ± 1.5	14.5  ± 1.3
LPE	0.8  ± 0.1	4.7  ± 0.6**	0.9  ± 0.1	1.5  ± 0.1**
PE	27.4  ± 2.0	23.2  ± 1.9*	29.9  ± 2.8	29.4  ± 2.6
PA	1.6  ± 0.1	1.4  ± 0.1	1.7  ± 0.2	1.9  ± 0.2

PI, phosphatidylinositol; PA, phosphatidic acid. Erythrocyte suspensions were washed and treated with Plase A₂ (10 units/ml) and their lipids were analyzed as described in Materials and Methods. Results are expressed as percentages of total phospholipids (mean ± SE, n = 3). Significant changes between control (untreated) and Plase A₂-treated cells are marked (*, P < 0.01; 

^**, P < 0.001).