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. 2012 Dec 7;12:156. doi: 10.1186/1471-2377-12-156

Table 1.

Logistic regression: variables predicting likelihood of high burden on caregivers of patients with ALS

Variable B S.E. Wald df p O.R. 95% CI for O.R.
Lower Upper
Abnormal behavior (CBI-R)
0.37
0.13
8.36
1
0.004*
1.44
1.13
1.85
Eating habits (CBI-R)
0.02
0.17
0.02
1
0.894
1.02
0.74
1.41
Stereotypic & motor behaviors (CBI-R)
0.10
0.11
0.79
1
0.376
1.10
0.89
1.36
Motivation (CBI-R)
0.04
0.06
0.34
1
0.555
1.04
0.92
1.18
Depression (DASS)
0.06
0.06
1.36
1
0.243
1.07
0.96
1.19
Anxiety (DASS)
−0.08
0.04
3.88
1
0.051
0.93
0.86
1.00
Stress (DASS)
0.12
0.052
5.10
1
0.024*
1.12
1.02
1.25
Bulbar (ALSFRS-R)
−0.07
0.08
0.76
1
0.384
0.93
0.79
1.1
Fine motor (ALSFRS-R)
−0.14
0.10
1.97
1
0.167
0.87
0.71
1.06
Gross motor (ALSFRS-R)
0.79
0.11
0.50
1
0.478
1.08
0.87
1.35
Respiratory (ALSFRS-R)
−0.00
0.11
0.00
1
0.975
0.10
0.80
1.24
Constant −2.11 1.22 2.99 1 0.84 0.121    

The caregiver burden was explained predominantly by the presence of abnormal behavior (in patients) and stress (in caregivers). * = statistically significant.