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. 2013 Jan 9;8(1):e53427. doi: 10.1371/journal.pone.0053427

Figure 5. AMPKα2 is necessary in the anti-fibrotic effect of DIM.

Figure 5

(A) Representative images of PSR staining form indicated groups. (B) Quantitative analysis of left ventricle interstitial collagen volume fraction in indicated groups (n = 6). (C) Real-time PCR analysis of the mRNA expression of TGF-β1, TGF-β2, collagen Iα, col1agen β and CTGF in the myocardium obtained from indicated groups (n = 6). The results were reproducible in three separated experiments. Data are expressed as means±SEM. *P<0.05 compared with the corresponding sham group. # P<0.05 vs KO+AB group.