Figure 8. Responses of VSM and PICC to neurogenic stimulation. A, B.
Neurogenic stimulation (EFS, 0.5 Hz) simultaneously evoked responses in PICC and VSM in the example shown. The PICC was quiescent pre-EFS but responded with several Ca2+-oscillations. The pre-EFS spontaneous activity in VSM was enhanced by 0.5 Hz. This was typical of 9/14 cells where EFS enhanced the frequency of VSM events as illustrated in the summary graph of panel G.