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. 2012 Oct 1;5:17. doi: 10.1186/1755-1536-5-17

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Copyright ©2012 Hanaoka et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Chest computed tomography and H & E staining microscopic images for case 1. Upper panel: emphysematous change in the upper zone of the lung (a), fibrotic lesion at the lung base (b), and the cancer shadow (arrow) at the right inferior lobe (c). Lower panel: positions (arrows) of sampling in the emphysematous lesion and the fibrotic lesion in the right inferior lobe without cancerous lesions (d), and the H & E staining microscopic images of specimens of the emphysematous lesion (e) and the fibrotic lesion (f).