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. 2013 Jan 9;8(1):e53414. doi: 10.1371/journal.pone.0053414

Table 1. IL-17A, IFN-γ and Foxp3 mRNA levels correlate in small intestinal mucosa of patients with untreated celiac disease (Untreated CD) but not in symptom-free celiac disease patients on gluten-free diet (Treated CD).

Untreated CD Treated CD
mRNA species compared: r P-value r P-value
IL-17A versus IFN-γ1 0.532 0.05 2 0.01 NS3
IL-17A versus Foxp3 0.61 0.02 0.10 NS
IL-17A versus IL-10 0.42 NS 0.20 NS
IL-17A versus TGF-β1 0.12 NS 0.18 NS
Foxp3 versus IFN-γ 0.02 NS 0.38 NS
Foxp3 versus IL-10 0.27 NS 0.17 NS
Foxp3 versus TGF-β1 0.04 NS 0.52 0.02
1

mRNA expression levels were compared in each individual sample.

2

r- and P-values obtained by correlation analysis between indicated mRNA species as determined by two-tailed Spearman rank correlation test.

3

NS = not significant, P-value >0.05.