Table 1.
Clinical characteristics of laparoscopic radical prostatectomy cases treated with or without neoadjuvant hormonal therapy groups *p < 0.05
| Variables | LRP* alone | LRP with NHT** |
|---|---|---|
| No. of patients |
270 |
72 |
| Mean age ± SD |
66.3 ± 6.1 |
67.7 ± 5.4 |
| Mean serum PSA ± SD, ng/mL |
8.64 ± 5.2 |
9.81 ± 4.1 |
| Biopsy Gleason grade, n(%) | ||
| ≤ 3 + 3 |
121 (44.8) |
30 (41.7) |
| 3 + 4, 4 + 3 |
85 (31.5) |
25 (34.7) |
| ≥ 4 + 4 |
64 (23.7) |
17 (23.6) |
| Clinical stage, n(%) | ||
| cT1c |
100 (37.0) |
27 (37.5) |
| cT2 |
170 (63.0) |
45 (62.5) |
| D’Amico risk classification, n(%) | ||
| low |
76 (28.1) |
14 (19.4) |
| intermediate |
74 (27.4) |
24 (33.3) |
| high |
120 (44.4) |
34 (47.2) |
| Pathological stage, n(%) | ||
| pT2 |
193 (71.5) |
62 (86.1) |
| pT3 |
77 (28.5) |
*10 (13.9) |
| Median operative time, min |
260 (121–572) |
276 (151–454) |
| Median blood loss, ml |
600 (50–4500) |
600 (90–3928) |
| Intraoperative complication | ||
| Rectum injury, n(%) |
4 (1.48) |
2 (2.78) |
| Blood transfusion, n(%) |
4 (1.48) |
2 (2.78) |
| Open surgery conversion, n(%) |
10 (3.70) |
3 (4.17) |
| Positive surgical margin, n(%) |
114 (42.2) |
*20 (27.8) |
| Biochemical recurrence, n(%) | 48 (17.8) | 14 (19.4) |
Patient characteristics and outcomes in laparoscopic prostatectomy (LRP) only and LRP with neoadjuvant hormone therapy (NHT) *p < 0.05.
LRP*: laparoscopic radical prostatectomy NHT**: neoadjuvant hormonal therapy.