Table 3.
Comparison of neoadjuvant hormonal therapy on the outcome of laparoscopic radical prostatectomy
| References | Period of NHT* (months) | No. of patients | Transfusion rate (%) | PSM** rate (%) | BCR*** rate after 2 years (%) |
|---|---|---|---|---|---|
| Rassweiler et al. [14] | |||||
| NHT group |
NA |
42 |
46.0 |
NA |
NA |
| non-NHT group |
- |
138 |
NA |
NA |
NA |
| Gregori et al. [15] | |||||
| NHT group |
less than 3 |
21 |
NA |
NA |
NA |
| non-NHT group |
- |
59 |
NA |
NA |
NA |
| Brown et al. [7] | |||||
| NHT group |
less than 3 |
5 |
0 |
0 |
NA |
| non-NHT group |
- |
60 |
1.7 |
17.0 |
NA |
| Maldonado-Valadez et al. [16] | |||||
| NHT group |
3.5 |
50 |
36.0 |
18.0 |
NA |
| non-NHT group |
- |
50 |
52.0 |
16.0 |
NA |
| Pu et al. [6] | |||||
| NHT group |
3 |
25 |
32.0 |
12.0 |
NA |
| |
8 |
19 |
31.2 |
10.5 |
NA |
| non-NHT group |
- |
11 |
36.4 |
45.5 |
NA |
| Our series | |||||
| NHT group |
3 or less |
47 |
2.12 |
27.7 |
27.7 |
| |
more than 3 |
25 |
4.00 |
28.0 |
4.00 |
| non-NHT group | - | 270 | 1.48 | 42.2 | 17.8 |
Reviews of the impact of NHT prior to LRP on operative and postoperative parameters.
NHT*: neoadjuvant hormonal therapy PSM**: positive surgical margin BCR***: biochemical recurrence.
NA: not available PSM: positive surgical margin BCR: biochemical recurrence.