Table 2. Meta-analysis of observational data on antibiotic (AB) susceptibility (in %) in children with severe acute malnutrition (SAM) or not only SAM (Mixed-NUT).

Author	Country	N	Age	Bacterial antibiotic susceptibility (%)a
			Mths	AMX	CTX	GEN	AGE	CHL	CIP	CRO	COA
SAM only
Babirekere [33]	Uganda	134	6–24	23.3	6.7	33.3	-	60	97	100	-
Bachou (HIV+) [34]	Uganda	30	12–24	53	21	78	-	55	93	84	56
Bachou (HIV−) [34]	Uganda	39	12–24	31	23	81	-	36	93	90	51
Berkley (SAM subgroup) [35]	Kenya	1182	7–35	57	42	-	87	77	-	94	-
Caksen [36]	Turkey	31	1–30	-	17	100	-	-	82	82	-
Mirabeau [37]	Nigeria	203	<60	-	-	85	-	-	-	61	-
Noorani [38]	Kenya	91	<60	-	-	80	-	-	80	80	-
Rabasa [39]	Nigeria	194	3–60	-	22.7	77	-	-	-	-	22.7
Reed [40]	S. Africa	863	<60	-	-	-	95.8	-	-	-	-
Median				42	22	80	91.4	57.5	93	84	51
IQR †				27–55	17–23	77–85	87–96	46–69	82–93	80–94	23–56
Population Weighted * mean (Meta-analysis):				52.9	35.4	72.8	90.7	73.7	90.0	89.3	30.7
Mixed-NUT. f
Bahwere [41]	Congo	779	1–16	14.3	79.3	100	-	20.7	-	100	-
Bejon(<14 d) [42]	Kenyad	690	<14 d	28	71	91	76b	81	99	95c	-
Bejon (>14 d) [42]	Kenyae	690	>14 d	28	39	73	76b	62	99	-	-
Berkley (All) [35]	Kenya	11847	7–35	59	54	-	88	81	-	93	-
Wolff (UTI) [43]	Multiple		<60	12	32	87	-	27	80	67	83
Median				28	54	89	76	62	99	94	83
IQR †				14–28	39–71	80–96	76–88	27–81	80–99	80–97	-
Population Weighted * mean (Meta-analysis):				53.5	55.5	88.5	86.7	76.7	99.0	93.5	83.0

^† IQR: 25–75 inter-quartile range.

^*Mean susceptibility weighed proportionally (coefficient) to number of patients (N) per study;

^a = Cumulated susceptibilities of all isolated bacteria. Abbreviations: AMX = amoxicillin (or ampicillin), CTX = co-trimoxazol, GEN = Gentamicin, AGE = AMX-GEN combination, CHL = chloramphenicol (^b 91% susceptible to CHL-GEN); CIP = Ciprofloxacin, CRO = Ceftriaxone (^c: in this case Cefotaxime instead, similar spectrum); COA = AMX-Clavulanate combination.

^d: age: <14 days of life,

^e: age>14 days of life.